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Chunk #33 — PRACTICAL ISSUES IN HARMONIZING EEG ANALYSES FOR GENETIC ANALYSES — Methodological issues

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Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity.
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information content in the frequency band definition. For our upcoming functional connectivity project, we have used such an approach. The Box 1 below explicates how this analysis was performed, with further specifics provided in the supplementary information. By using this approach, we decrease the heterogeneity induced by suboptimal frequency band definition, while increasing the stability of our estimates and power of our tests by averaging coherence across multiple frequencies.