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Chunk #20 — Results — Generation of Induced Pluripotent Stem Cells from 5 Alzheimer’s Patients

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Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells.
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We selected subjects from the GRECC Dementia Special Care Unit at the Bedford VA Hospital based on a clinical diagnosis of AD and the absence of other active medical problems. Some of them underwent brain imaging/PET scan to obtain more accurate diagnosis of AD. Brain tissues from two AD patients were obtained at autopsy, and neuropathological diagnosis of AD was confirmed (Table 1).