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Chunk #1 — Introduction

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Sex differences amongst dependent heroin users: histories, clinical characteristics and predictors of other substance dependence.
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There is some evidence of different characteristics for male and female dependent heroin users. Those studies that have reported sex differences found that females were younger (Chen, Shu, Liang, Hung, & Lin, 1998; Chiang, et al., 2007; Williamson, Darke, Ross, & Teesson, 2007) and had more suicide attempts and fewer completed suicides (Darke & Ross, 2002; Darke, Ross, Lynskey, & Teesson, 2004; Darke, Williamson, Ross, & Teesson, 2005); different injecting behaviours (Hoda, Kerr, Li, Montaner, & Wood, 2008); less education and employment (Chen, et al., 1998; Chiang, et al., 2007); a younger onset of heroin use (Chen, et al., 1998); more dysfunctional families and exposure to more unfavourable social factors (Chatham, Hiller, Rowan-Szal, Joe, & Simpson, 1999; Chiang, et al., 2007); greater health service utilization (Darke, Ross, Teesson, & Lynskey, 2003; Fletcher, Broome, Delany, Shields, & Flynn, 2003); higher standardised mortality ratios (Rehm, et al., 2005); more psychological problems (Chatham, et al., 1999; Mills, Teesson, Darke, Ross, & Lynskey, 2004); and were more likely to sustain abstinence after treatment (Darke, et al., 2007a) than men. The evidence regarding sex differences