Chunk #32 — Discussion

Source: Mining the human phenome using allelic scores that index biological intermediates.
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the major histocompatibility region [9]. In contrast, in the case of BMI, no single variant contributes disproportionately to explaining trait variance (Table S7), and so the explanatory power of the allelic scores is facilitated through the addition of many variants of small effect scattered across the genome [9], [11], [22].