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Chunk #25 — Results — Efficacy

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A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies.
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yes

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The bupropion + lozenge condition and the patch + lozenge condition were both compared to a composite monotherapy condition to determine whether either of the combination conditions was superior to monotherapy. Results of logistic regression analyses revealed that, relative to the monotherapies, patch + lozenge produced significantly higher initial cessation rates and EOT abstinence rates (see Table 3), using the Bonferroni-corrected p-value. There were no other differences between the combination conditions and the composite monotherapy condition. The results were similar after controlling for race, gender and site. It should be noted that there were no significant differences either between the two combination conditions or among the monotherapy conditions at any of the timepoints using the Bonferroni-corrected p-value.