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Chunk #60 — Online Methods — Comparison to other methods

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Partitioning heritability by functional annotation using genome-wide association summary statistics.
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yes

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the method is not intended to control for any other annotations, it had a high rejection rate for the null baseline simulations, detecting cell-type-specific signal where there was none. Thus, its high rejection rate for the cell-type-specific simulations were not reflective of true power. It remains a powerful method for traits with many significant SNPs, if the goal does not include controlling for other categories.