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Chunk #22 — Results — Time point-based network analysis — Cluster-based network analysis

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Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain.
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Hub genes, affiliated microRNAs and expression data for both (direction and time of change, nominal p value) are provided for each cluster. MicroRNAs preceded by a "+" superscript were not DE in our dataset but were added and connected by the IPA algorithm. Italics denote critical network genes (see Table 5). The last column of microRNA data lists several hub gene-connected microRNAs that were also dysregulated in prefrontal cortex of human alcoholics [10] and/or alcohol-dependent rats [9]. These microRNAs are provided as probeset IDs or microRNA names, depending on their presentation in the reference. The last column of mRNA data reports publications that demonstrate a link between ethanol exposure and expression changes for the given hub gene in each miRNA cluster. References are provided as a hyperlink and are prefixed with the abbreviation for the studied species.