In an effort to confirm the robustness of the continued significance of the association between early-onset dependence and subsequent suicide plans in the net effects model that includes all controls, this model was re-estimated separately among women and men and separately in the younger and older halves of the sample. The OR of dependence predicting plans remains elevated in all these sub-samples (2.3–8.3). We also re-estimated the net effects model to predict plans in such a way as to distinguish early-onset dependence that was active versus remitted at the time of the baseline interview. Both ORs are significant, but the OR for remitted dependence [3.9 (1.2–12.9)] is higher than the OR for active dependence [2.6 (1.1–6.0)], suggesting that the causal pathways linking dependence with subsequent suicide plans are for the most part not mediated by current tobacco involvement.
