Because 115 of 186 females who had consumed at least one alcoholic beverage in their lives reported never having been drunk and were not queried about maximum drinks, there is insufficient data to consider a genome-wide association for this trait or AD in females. For these 186 females who have consumed alcohol, flushing response was reported and rs671 is considered as a candidate locus and significantly associated with flushing response in females (p = 1.25×10-11).