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Chunk #19 — Results — Genome-Wide Association

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ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.
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Because 115 of 186 females who had consumed at least one alcoholic beverage in their lives reported never having been drunk and were not queried about maximum drinks, there is insufficient data to consider a genome-wide association for this trait or AD in females. For these 186 females who have consumed alcohol, flushing response was reported and rs671 is considered as a candidate locus and significantly associated with flushing response in females (p = 1.25×10-11).