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Chunk #29 — Results — Application to a meta-analysis of blood lipids combined with a liver expression dataset

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Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.
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Table 1 lists the previously reported lipid-eQTL for which we find strong support against the colocalisation hypothesis (PP3 >75%). The LocusZoom association plots for each of these loci can be found in Figure S5. In addition to the loci listed in Table 1, we found strong evidence of distinct signals between HLA-DQ/HLA-DR and TC (Table S1) but these results must be interpreted with caution owing to the extensive polymorphism in the major histocompatibility complex region.