(1996–2000). The third phase of telephone interviews (2001–2005) indexed smokers, drinkers, and controls from the older and younger cohorts. For 53% of our sample, self-reported ancestry for all grandparents was available. Ancestry was predominantly European with 93% having full European ancestry. Of these, 65% had full British and/or Irish ancestry and 94% had at least 2 grandparents of British and/or Irish decent.