Creation of a centralized database and repository for all phenotype and genotype data provides investigators with the opportunity to easily access the data as they identify new areas of interest for cross-study analyses. In GENEVA, once each study's genotype and phenotype data have gone through a standardized quality control cleaning process, the CC adds each study's phenotype data, data dictionary, individual-level consent and public use or GENEVA-only use status to a centralized relational database. As the WGs define common phenotypes and covariates for cross-study analyses, the CC applies study-specific algorithms to each study's phenotype data to create a dataset and data dictionary for the harmonized variables and covariates, and these are added to the centralized relational database.
