Keyword searches were conducted in Pubmed, ISI Web of Knowledge, and Google Scholar using the terms “alcoholism,” “alcohol abuse,” “alcohol,” “brain,” “atrophy,” “volume,” “white matter,” “adolescent,” and “magnetic resonance imaging.” Abstracts were examined for references to brain volumes in AUDs, and the full text of the study was retrieved if it appeared relevant. Reviews on structural brain changes in AUDs were examined for additional citations [e.g., (Bühler and Mann, 2011; Crews and Nixon, 2009; Sullivan and Pfefferbaum, 2005)].