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Chunk #63 — 4. Discussion — 4.3 Alcohol effects and family history of alcoholism

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Response to alcohol in women: role of the menstrual cycle and a family history of alcoholism.
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the present study, based on other subjective measures, such as ratings of Drug Strength, there was no evidence that FHP women had a reduced subjective response to alcohol than FHN women and these results are consistent with a previous study from our laboratory (Evans and Levin, 2003). Among the studies that have measured the effects of alcohol on performance in FHP and FHN women, there has been some evidence that FHP women are less impaired by alcohol on either the DSST (Evans and Levin, 2003; Lex et al., 1988) or a measure of motor coordination (Eng et al., 2005; Evans and Levin, 2003; Lex et al., 1988). For instance, in the study by Eng et al. (2005), 25 FHN and 25 FHP women were administered a single dose of alcohol (0.75 g/kg); FHP women tended to be less impaired on body sway, but these modest effects were only observed after various transformations of the raw data. The present study confirms and extends these findings in that FHP women were significantly less impaired by alcohol on the balance task (our gross measure of motor coordination) than FHN women, but the effect was modest.