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Chunk #4 — Introduction

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Time to First Morning Cigarette and Risk of Chronic Obstructive Pulmonary Disease: Smokers in the PLCO Cancer Screening Trial.
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Lung function testing is the gold standard for COPD diagnosis but clinical guidelines [15] advise against screening asymptomatic patients for COPD with due to the associated costs [16]. Thus, asymptomatic smokers may easily be missed; a single question, such as TTFC, which could be used as a screening tool for COPD risk in smokers would be cost-effective in terms of time and economic and healthcare resources.