whether they currently use medication, classification performance improved remarkably: Medicated OCD patients and healthy controls could then be distinguished with a 0.73 AUC (SD = 0.03, p corr < .001) (in contrast to unmedicated OCD and healthy controls, with 0.61 AUC [SD = 0.02, p corr = .03]), and medicated and unmedicated OCD patients with 0.86 AUC (SD = 0.02, p corr < .001). These multivariate results therefore mirror the univariate results, and highlight that medication use is associated with significant differences in brain anatomy.
