After multivariate adjustment for centre or country and classic cardiovascular risk factors (age, tobacco consumption, years of education, level of physical activity, systolic blood pressure, apolipoprotein A-1 and apolipoprotein B concentration, waist circumference, and treatment for hypertension, diabetes, and dyslipidaemia), alcohol consumption patterns remained associated with the occurrence of hard coronary events, regardless of country (Belfast P<0.02; France P<0.02; and in all centres P<0.001; global Wald χ2 test; fig 1 ). Conversely, alcohol intake was not associated with incidence of angina pectoris.