The method presented should be transferable to settings other than that in Iceland if certain conditions are met and with proper adjustments (Supplementary Note). Long-range phasing and IBD detection do not require explicit knowledge of the genealogy. However, the number of individuals genotyped has to be above a certain threshold. While many factors play a role, we speculate that having as little as 1% of a population genotyped may be adequate for the method to yield useful results. This would still correspond to a very big sample size for a large population, but it may be attainable in less than a decade given the fast pace in technological advance. This could be achievable in the near future, or already achieved, for smaller populations, including isolated regions within a large nation. Indeed, the results shown here are particularly relevant for the planning of biobanks. The genealogy plays an important role in the imputation of untyped individuals. Still, even without it, haplotypes could be imputed into a proband if the mate and at least one child are genotyped, with the other relatives
