Finally, the male PTSD-PGC2 sample was examined separately by its components, PTSD-PGC1.5 (n ~ 30,000) and UK Biobank [UKB] PTSD data (n ~ 55,000; which comprise PTSD-PGC2) given recent findings that in males, significant heritability estimates were found in UKB data but not PTSD-PGC1.5 (Nievergelt et al., 2019), which would then impact genetic correlation estimates, as heritability must be demonstrated for LDSC to be conducted.
