Chunk #22 — RESULTS — Functional integration of human iN cells into mouse brain

Source

Rapid single-step induction of functional neurons from human pluripotent stem cells.

Embedded

yes

Text

To probe the competence of Ngn2-induced iN cells to form synapses in vivo and not only in vitro, we injected EGFP-labeled iN cells on day 6 into the striatum of newborn mice (postnatal day 2), and analyzed the mouse brains six weeks later.