In an early study, Salimov (1999) examined the AA vs. ANA, P vs. NP, HAD1 vs. LAD1 and HAD2 vs. LAD2 rat line-pairs, as well as several mouse lines with differences in ethanol intake, for anxiety-like behaviors (several measures with the elevated cross-maze and inescapable slip funnel tests). A factor analysis was conducted to see where the respective lines scored on the dimension/factors generated. Although a factor analysis increases the complexity of interpretation, since interpretation is not based on the raw data itself; it is instructive that the HAD1 and HAD2 lines had significant separation in factor scores from the LAD1 and LAD2 lines for factor 1, whereas the AA and P lines had significant separation from the ANA and NP lines, respectively, for factor 2. Thus, the HAD1 and HAD2 line-scores clustered together on factor 1, and the AA and P line-scores formed a separate cluster on factor 2. Given that the HAD-LAD replicate pairs were generated from the same N/Nih foundation stock and the AA-ANA as well as P-NP lines had Wistar lines as their foundation stock, this
