tissue are subject to different ethical constraints that manifest as relatively long and highly variable postmortem intervals.62 In contrast, NHP experiments can be performed in a highly controlled and more timely fashion. Finally, NHPs have resisted the widespread application of modern genetically coded tools. Single cell technologies, including snRNA-Seq and snATAC-Seq can identify cell types and potent regulatory sequences that will break this resistance and enable the effective applications of genetically coded tools in large, wild type animals that resemble humans. Rhesus macaque behavior is readily interpretable in terms of human behavioral theory such as economic theory,63-66 learning theory,67 and even game theory.68,69 The diversity of MSN cell types presented here provides a blueprint to investigate the cell-type-specific mechanisms for such sophisticated behaviors.
