Chunk #227 — VIII. A possible underlying neurobiology: connectivity constellations — B. Quality and/or quantity of connections involved in vulnerabilities
Twin methods also provide data that links these heritable determinants of brain volume to heritable determinants of cognitive functions that include memory and estimates of different aspects of cognitive function [246, 247] In one of the largest available twin datasets, virtually all of the heritable individual differences in brain regional volumes could be attributed to genetic influences shared with influences on cognitive abilities (measured primarily by memory tasks) [247]. In another twin dataset, the overwhelming majority of genetic influences on frontal lobe brain volume were shared with those that influence cognitive ability measured primarily by tests of executive function [117].