Over the past three decades our understanding of the factors that contribute to and the consequences of schizophrenia and alcohol-related brain damage (ARBD) has been advanced through studies of neuroimaging, neuropsychology, genetics, and neuropathology of the human brain. In particular, the field of neuropathology has been transformed by the molecular techniques of the so-called genomic age (Sutherland, Sheedy, & Kril, 2014). For the past decade many of these studies have been facilitated by the New South Wales Brain Tissue Resource Centre (NSWBTRC), a specialized research resource, supported by the National Institutes of Alcohol Abuse and Alcoholism and Schizophrenia Research Institute (Australia), and established to provide clinically and pathologically characterized post-mortem brain tissue to researchers.