No significant differences were observed between the schizophrenia and control participants in terms of either their FA or Mode in the visual fibers of the corpus callosum. Although this is the first DTI study (to our knowledge) that has specifically investigated for diffusion abnormalities in these particular fibers, the null result is consistent with the majority of studies that have investigated for diffusion abnormalities in primary sensorimotor fibers in schizophrenia patients in schizophrenia patients (e.g., Schneiderman et al., 2009; Shergill et al., 2007). In contrast, diffusion abnormalities in general, and FA abnormalities in particular, have consistently been observed in the white-matter fasciculi that either connect the frontal lobes (e.g., genu of the corpus callosum; Whitford et al., 2010b) or project from the frontal lobes, including the uncinate (Burns et al., 2003), arcuate (Phillips et al., 2009), superior longitudinal fasciculus (Karlsgodt et al., 2008) and cingulum (Kubicki et al., 2003). A recent meta-analysis by Ellison-Wright et al., (2009) of fifteen voxel-based DTI studies also reported evidence for abnormalities in frontally-projecting fasciculi in patients with schizophrenia. In contrast, however, while Kanaan et
