In a model to assess sedative response across timepoints following ethanol infusion (the +110 through +230 timepoints), the three-way dose by impulsivity interaction was significant (num df = 4.66, ATS = 4.65, p < 0.001). As can be observed in Figure 2, among less impulsive participants, sedative response continued to be stronger in the high dose than in the low dose condition. Sedative response also declined steadily following the end of ethanol infusion among less impulsive participants. However, the decline in sedative response was less consistent among more impulsive participants after the end of infusion.
