All recruited individuals and participating family members were administered a validated poly-diagnostic instrument, the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) [Bucholz et al., 1994; Hesselbrock et al., 1999]. The SSAGA allows assessment of alcohol dependence by several criteria, including Feighner [Feighner et al, 1972], DSM-IIIR [American Psychiatric Association, 1987], DSM-IV [American Psychiatric Association, 1994], and ICD-10 [World Health Organization, 1993].