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Chunk #35 — Discussion — Genetic signals in the genome-wide analysis of RDC schizoaffective disorder, bipolar type data-set

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Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
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which are signalling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle and oncogenic transformation; GRIK2 encoding glutamate receptor, ionotropic kainate 2 precursor (glutamate receptor 6) (GluR-6) (GluR6); and CDH12 encoding cadherin 12, type 2 preproprotein, a type 2 classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell–cell adhesion. It will require substantial additional work by us and others in order to confirm which of the polymorphisms showing strong association within the current study influence risk of illness.