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Chunk #17 — Results — Association with symptom count

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A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
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Results for the entire genome are summarized in the Manhattan plot (Figure 2). After correcting for inflated, 72 SNPs of 591,685 genotyped autosomal SNPs tested showed evidence of association with symptom count with inflation corrected p values <10−4 (Table S2). None of these 72 SNPs reached genome-wide significance. Among these top signals, we identified 7 chromosomal loci containing 3 or more SNPs within 50 kb of each other that show association with SC (Table 1).