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Chunk #39 — Methods — Genotyping, imputation, and quality control — CHS

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Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
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CHS genotyped 3,980 participants free of cardiovascular disease at baseline with available DNA and consent to genetic testing. After exclusions for call rate <95%, sex mismatch, or discordance with prior genotyping, 3,291 white participants remained. Of these, 3,140 had pulmonary function measures and complete covariate information.