In the 44-year study period, 545 individuals (1.48%) from the OCD cohort had died by suicide, and 4297 (11.68%) had attempted suicide at least once. Individuals with OCD had an increased risk of both dying by suicide and attempting suicide compared with the matched controls (OR=9.83 (95% CI, 8.72–11.08) and OR=5.45 (95% CI, 5.24–5.67), respectively; Table 1). When adjusting for psychiatric comorbidities, the risk of dying by suicide was slightly reduced—especially when substance use disorders and affective disorders were taken into account—but remained substantial (ORs ranging from 7.49 to 9.23). On the other hand, the risk of attempted suicide was substantially reduced, although not eliminated, when adjusting for comorbidities (ORs ranging from 1.90 to 4.21). Adjusting for parental level of education did not change the risk estimates (Table 2).
