This paper focuses on SOB and its interaction with dopamine receptor genes and gender. It is part of a larger series of studies examining the associations of genetic polymorphisms of the dopamine system with behavior [53], [54]. In this case, we examined how SOB was associated with measures of sensation seeking, impulsivity and reproductive behaviors, as well as the interaction between SOB, gender, DRD2 and DRD4 polymorphisms in influencing these behavioral outcomes. The phenotypes were evaluated using the Sociosexual Orientation Inventory (SOI), Barratt Impulsivity Scale (BIS), Eysenck Impulsivity Questionnaire (EIQ), Sensation Seeking Scale (SSS), and Delay Discounting Task (DDT). Additional phenotypes considered included self-reported virginity status, age at first sexual intercourse, and desired age at first birth. Three independent scales (BIS, EIQ, and DDT) were used to assess impulsivity because of the heterogeneous nature of impulsivity [reviewed in 54]. This is the first such study we are aware of to examine the interactions between SOB and dopamine genetic polymorphisms on normal behavioral variation in a non-clinical population.
