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Chunk #6 — RESULTS — Replication of cis-eQTL signals in three independent data sets

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Genetic variability in the regulation of gene expression in ten regions of the human brain.
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cis-eQTL replication rates were similar between exon-specific and gene-level signals but were reduced for signals where the marker was further away from its target gene (Supplementary Table 3), a phenomenon we attribute to the larger number of tests that belong to this group. Therefore, to increase confidence in our analyses of eQTL location, we considered only those signals that replicated in one of our replication data sets.