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Chunk #47 — Discussion

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Clinical, Functional, and Biological Correlates of Cognitive Dimensions in Major Depressive Disorder - Rationale, Design, and Characteristics of the Cognitive Function and Mood Study (CoFaM-Study).
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Second, the often observed psychosocial and functional decline and inability to recover after an acute episode of depression to premorbid functioning requires a better understanding of the mediators of functional decline. The CoFaM Study will address this key question by investigating the mediating role of the three cognitive dimensions in functional impairment decline in depression. A possible outcome of this study might be a better understanding of this crucial relationship, and the research might provide new leads into improving psychosocial functioning in the future.