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Chunk #61 — 4. Discussion — 4.5. Genetic Factors underlying P3 and Risk for Alcoholism and Related Disorders

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Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task.
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onset of regular drinking (Chorlian et al., 2013), and trajectories of drunkenness (Dick et al., 2014). While heritability of the reward-related P3 is yet to be determined, it may be another promising endophenotype, as both alcoholics (Kamarajan et al., 2010) and HR offspring (in the current study) manifest lower P3 amplitude.