Thus, the comorbid individuals in the current analysis of the COGA sample may be in a different and more severe stage of their comorbid disorder than individuals with CU and bipolar disorders. In this stage, CUD may be more often co-occur with another SUDs and may be less related to comorbid anxiety disorders. The CUD diagnosis indicates that comorbid individuals have not only a frequent CU but also mental and physical consequences due to the use, withdrawal symptoms and problems to stop or control use. These characteristics may be more strongly associated with the risk of other alcohol- and SUDs rather than anxiety symptoms and disorders.
