As described in the original cohort profile,1 the overall objective of TRAILS is ‘to contribute to the understanding of the determinants of adolescents’ mental (ill-)health and social development during adolescence and young adulthood, as well as the mechanisms underlying the associations between determinants and outcomes’. This aim still leads in all TRAILS-related activities and investments. The changes described in this update mainly refer to the enrichment of the database with two new data collection waves covering a different life phase; and additional variables such as psychiatric diagnoses, registry-recorded care utilization and genome-wide SNP variations.
