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Chunk #31 — Discussion

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Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
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This study employed careful and comprehensive phenotyping; MD and PhD-trained psychologists conducted all assessments and recruitment sites used the same assessment approach and all cases were reviewed at a single site (JHU) to ensure diagnostic replicability. Given the likely etiologic heterogeneity of OCD, the comprehensive phenotyping provides opportunities for future studies (through subtyping based e.g. on factor-analytical approaches).