Thirty-two male and nine female patients, aged 39–83 years (mean 65 years) diagnosed with ESCC (n = 14), esophageal adenocarcinoma (n = 19), or gastric adenocarcinoma (n = 8) were randomly selected among the patients which underwent primary surgery at Lund University Hospital, Sweden, during 2001–2005 (Supplementary Table I). None of the patients had received neoadjuvant radiotherapy or chemotherapy. Biopsies were taken from the normal and carcinoma-afflicted part of the removed tissues and directly snap-frozen. Written informed consent was provided by all patients, and the study was approved by the Lund University ethics committee. Results presented in Figures 1, 5 and 6 were obtained from biopsies randomly selected among the ESCC patients.
