In conclusion, the vulnerability to alcohol effects and AUDs may be associated with a modulation of excitability of some neural circuits more than others. These changes affect networks associated with cognitive domains of attention and self-monitoring that are part of the rubric of the frontal executive function which is impacted with both acute and chronic alcohol use. Both ERP and ERO studies discussed here provide evidence for impaired attention, response inhibition, and monitoring functions. Source localization of these components highlights impaired loci in frontal lobes, suggesting the utility of a multimodal approach. Future studies that integrate neuroelectrophysiology and neuroimaging are essential to understanding these complex structure–function interactions.
