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Chunk #7 — Methods — Paradigm

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The Detection of Phase Amplitude Coupling during Sensory Processing.
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Participants performed an engaging sensory paradigm (Figure 1), designed to elicit patterns of high-frequency oscillatory activity. Each trial started with a variable fixation period of 1,500, 2,500, or 3,500 ms randomized across trials, followed by the presentation of a visual grating or auditory binaural click train stimulus; however only the visual data will be analyzed in this article. The visual grating stimulus had a spatial frequency of two cycles/degree and was presented for 1,500 ms. To keep participants engaged with the task, cartoon pictures of aliens or astronauts were presented after the visual grating, for a maximum of 500 ms. Please note that visual responses to the alien or astronaut picture did not form part of the MEG analysis. Participants were instructed to respond to the appearance of an alien picture using a response pad (maximum response period of 1,500 ms). The accuracy of the response was conveyed through audio-visual feedback, followed by a 500 ms fixation period. In total, the MEG recording lasted 12–13 min and included 64 trials with visual grating stimuli. Prior to MEG acquisition, the nature