To identify transcripts that were similarly regulated by cocaine, cannabis and phencyclidine, we again employed GAP scores to examine 24 Group I–II cases with a confirmed drug abuse history and toxicological evidence of cocaine, cannabis or phencyclidine (COC+, THC+ and PCP+, respectively) present at death. This identified 160 transcripts shared between the COC+, THC+ and PCP+ groups ( Fig. 2B ). Additionally, 474 transcripts were shared by the COC+ and PCP+ groups, 83 transcripts by the COC+ and THC+ groups, and 146 transcripts by the PCP+ and THC+ groups. A total of 964, 299 and 1152 transcripts were exclusively changed in the COC+, THC+ and PCP+ groups, respectively. The lower total number of transcripts identified for cannabis cases was noteworthy.
