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Chunk #31 — Discussion

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Assessment of a modified DSM-5 diagnosis of alcohol use disorder in a genetically informative population.
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addition does not significantly inflate prevalence (e.g., Agrawal et al., 2011; Keyes et al., 2011). Given the modest change in prevalence under different DSM criteria, and particularly the quite minor effects of the “loss” of individuals who endorsed only the LP criterion, the consistency of the alcohol diagnoses from DSM-IV to DSM-5 is reasonable (kappa=0.86). However, this obscures potentially important qualitative differences among those meeting only DSM-IV or DSM-5 criteria.