To examine the relationship between lifetime MDD status and frontal EEG asymmetry, a full factorial mixed linear model (SAS 9.2) was performed. Lifetime MDD status (past and/or current MDD = lifetime MDD+, never depressed = lifetime MDD-) and biological sex (male, female) were centered between-subjects variables, whereas visit day (4), reference (4: AVG, CSD, Cz, and LM), and channel (4: F2-F1, F4-F3, F6-F5, F8-F7) were within-subjects variables. EEG asymmetry score based on total 8-13 Hz alpha power was the dependent variable.4 Cohen's d is reported for significant differences between lifetime MDD groups.
