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Chunk #58 — Discussion

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Increased intra-participant variability in children with autistic spectrum disorders: evidence from single-trial analysis of evoked EEG.
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When analyzing the data presented here, significant attempts were made to minimize potential confounds that could artificially inflate the estimates of variability in one group or another. Note that the within-subject estimates of variability reported here are normalized, thus validating group comparisons; note also that the two groups of participants were well matched as regards to age, IQ, and gender, and that the data from the two groups was matched in terms of quality. It is therefore unlikely that methodological factors contributed to the group differences reported here. However, as is outlined in the methodology, data is not reported from all participants who participated in the study. This was driven primarily by the goal of ensuring well matched samples, but was also a consequence of the fact that not all participants generated an IC that was considered reliable enough to be analyzed. The most likely reason for this is that only a small amount of data (approximately 51/2 min of data per participant) were recorded and available for ICA decomposition. The experiment was necessarily short given the age of the