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Chunk #19 — Results — 5-HTTLPR effects on BSI anxiety

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Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.
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In the severe vs. low anxiety comparison, Bayesian odds ratio estimation showed firm credible intervals for the ss vs. ll (ORBayesian = 1.31–1.39) effects, in the total population (Fig. 2). Results indicate a remarkable difference between the younger (≤30 years) and the elder (>30) subpopulations (supporting traditional PLINK results). In the elder subpopulation the effect of the ss compared to ll genotype of 5-HTTLPR is modest (ORBayesian = 1.13–1.19), in the younger subpopulation, however, the effect is strong with a firm credible interval ORBayesian = 1.55–1.82 (Fig. 2).