All patients were recruited within 6 months after the diagnosis and tests were repeated at inclusion. Follow-up visits were carried out on a yearly basis as part of the routine visits, with serial cognitive tests, which included MMSE and ACE and the NPI, MDI, ADCS-ADL, and CDR scales. Clinical progression of MCI to AD was determined based on whether the patient clinically fulfilled the NIA-AA criteria (McKhann et al., 2011). If a patient with MCI progressed to another diagnosis than AD, they were excluded from the comparison between pMCI and sMCI.
