mapping QTLs responsible for the excessive drinking of mice that are heterozygous for the C57BL/6J and FVB/NJ alleles when compared to those that are homozygous for one or the other allele. To do this, the genome was searched for individual QTLs showing overdominance in a C57BL/6J X FVB/NJ F2 population. Our initial results have identified three QTL regions showing overdominance in the expected direction (Phillips et al. 2010).