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Chunk #33 — Results — Copy Number Variation — Very large copy number variants

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A genome-wide investigation of SNPs and CNVs in schizophrenia.
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the Illumina Human610-Quad BeadChip revealed a further 6 deletions >500 kb (Heinzen et al., in preparation), suggesting that it is a risk factor for other neuropsychiatric conditions as well as schizophrenia. Collectively, these data strongly suggest that deletions in this regions contribute to schizophrenia and epilepsy, providing another example of a CNV influencing different neuropsychiatric conditions [38], and supporting the observation that deletions greater than 2 Mb are likely to be disease-associated.