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Chunk #73 — Discussion — Study goals and findings

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A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study.
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This study identified no evidence for consistent lateralization among the factor loading patterns and no overriding regional involvement. Furthermore, this study identified no clear inter-relationships among spectral bands, number of coherences per factor, nor increased or decreased coherence. A primary spectral finding was the dominance of slow beta across all conditions with the majority of factors manifesting peak loadings in the slow beta range and far fewer in the fast beta, theta, alpha and delta ranges, a finding of uncertain clinical significance. Earlier studies which demonstrated findings specific to differing scalp regions and spectral ranges may largely reflect methodological differences as discussed in the Background.